Stressed !!!

Bree medication was recently increased from 200mg twice a day to 300mg and we're all paying the price. While it seemed to control her seizures it has also increased her irritability to a new level. She's constantly screaming and crying and will wake up several times a night for hours at a time. One minutes she'll be smiling and playing with her toys and the next she's screaming at the top of her lungs and nothing will stop her. Paige doesn't seem to be bothered by her sister's cries, but she will wake up at night if her sister cries long enough. Connor's constantly asking why sissy is so sad and I don't know what to tell him. I thought the irritability was just from teething but I have yet to see any teeth. Deep down I know it's the Keppra and I'm scared how long this will last. My guess is that as long as she's on this dose she will continue to be this way. I tried calling the neuro on Friday will no luck. There has to be something we can give her to make her happy again.